“Companion. Protector. Killer.”
A genetic research facility worker exposes animal abuses there to a local TV reporter, who frees and takes in a genetically altered dog from the lab, unaware that he has a violent streak.
Director: John Lafia
Watch NowStream Man's Best Friend now in HD quality.
Ally Sheedy
Lori Tanner
Lance Henriksen
Dr. Jarret
Robert Costanzo
Detective Kovacs
Fredric Lehne
Perry
John Cassini
Detective Bendetti
J.D. Daniels
Rudy
William Sanderson
Ray
Trula M. Marcus
Annie
Robin Frates
Judy Sanders
Rick Barker
Mailman
Bradley Pierce
Chet
Robert Arentz
EMAX Security Guard
Cameron Arnett
Dog Catcher #1
Adam Carl
Dog Catcher #2
Thomas Rosales Jr.
Mugger
2008
2025
2001
1941
1978
2024
2019
2010
1979
1995
1974
2014
1980
2024
2007
2006
1999
2019
2020
2012