Call Jane

Elizabeth Banks

Joy

Sigourney Weaver

Virginia

Chris Messina

Will

Wunmi Mosaku

Gwen

Kate Mara

Lana

Cory Michael Smith

Dean

Grace Edwards

Charlotte

John Magaro

Detective Chilmark

Aida Turturro

Sister Mike

Emily Creighton

PTO mom

Gina Jun

Reporter

Rebecca Henderson

Edie

Bianca D'Ambrosio

Erin

Alison Jaye Horowitz

Sandra

John Rothman

Director McDonald

Geoffrey Cantor

Dr. Falk

Evangeline Young

Maeve

Beau Baxter

Dr. Aaronson

Joel Brady

Dr. Campbell

Maia Scalia

Marion